Saving Advanced Settings error

When i save the advanced settings i get the following error:

Warning: fopen(C:/wampserver/www//1-Ontwikkeling/Dolphin-v.6.1.4-Free/inc/params.inc.php) [function.fopen]: failed to open stream: Permission denied in C:\wampserver\www\1-Ontwikkeling\Dolphin-v.6.1.4-Free\inc\admin.inc.php on line 1234

Warning: fwrite(): supplied argument is not a valid stream resource in C:\wampserver\www\1-Ontwikkeling\Dolphin-v.6.1.4-Free\inc\admin.inc.php on line 1237

I know it's been over 1 year now since you were experiencing this issue. However, I am having similar issue and I amn wondering if you can help me. When I click on Save button on "Advanced Settings" page (in Admin) I get Error 400.

Any help would be much appreciated.

Thanks!